Immunological aspects of bacterial keratites in patients with diabetes mellitus

Background. The purpose was to analyze the cytokine balance of lacrimal fluid in patients with bacterial keratitis and diabetes mellitus (DM) at first visit identify immunological aspects disease. Materials methods. analysis pro- anti-inflammatory concentration performed 17 type 1 DM 15 nondiabetic visit. Data from 14 healthy individuals were used for comparison. In addition standard ones, ophthalmic examination methods included bacteriological examination, fluorescein test, anterior segment optical coherence tomography, non-contact corneal aesthesiometry. levels interleukin (IL) 1β, IL-6 IL-10 sick contralateral eye determined by a quantitative colorimetric enzyme-linked immunosorbent assay using ELISA kits. Results. keratitis, IL-1β exceeded that (p < 0.05) did not differ significantly > 0.05). level corresponding indicators those Conclusions. have features